Comprehensive Evaluation Model of DNA Codewords Based on Combined Weight Method

Author

Wang, Yan-Feng ; Niu, Ying ; Zhang, Xun-Cai ; Cui, Guang-zhao

Author_Institution

Coll. of Electr. & Electron. Eng., Zhengzhou Univ. of Light Ind., Zhengzhou

fYear

2007

fDate

14-17 Sept. 2007

Firstpage

254

Lastpage

257

Abstract

An evaluation problem of codewords for DNA computing was studied. The constraints on codewords design were discussed, five evaluation criteria: distance constraint, GC-content, continuous bases, melting temperature and free energy were presented. According to the correlation of the criteria, the combined weight method, which based on statistics principle was proposed, and then a comprehensive evaluation model for evaluating DNA codewords, was also developed. The simulation result showed the feasibility and validity of the comprehensive evaluation model.

Keywords

biocomputing; statistics; DNA codewords; DNA computing; GC-content; combined weight method; comprehensive evaluation model; continuous bases; distance constraint; free energy; melting temperature; statistics principle; Algorithm design and analysis; Computer industry; DNA computing; Educational institutions; Electronics industry; Industrial electronics; Sequences; Stability; Statistics; Temperature;

fLanguage

English

Publisher

ieee

Conference_Titel

Bio-Inspired Computing: Theories and Applications, 2007. BIC-TA 2007. Second International Conference on

Conference_Location

Zhengzhou

Print_ISBN

978-1-4244-4105-1

Electronic_ISBN

978-1-4244-4106-8

Type

conf

DOI

10.1109/BICTA.2007.4806462

Filename

4806462