Abstract :
Notice of Violation of IEEE Publication Principles
"Estimating neutral divergence amongst Mammals for Comparative Genomics with Mammalian Scope"
by Anup Bhatkar and J.L. Rana
in the Proceedings of the 9th International Conference on Information Technology (ICIT\´06)
After careful and considered review of the content and authorship of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE\´s Publication Principles.
This paper contains significant duplication of original text from the papers cited below. The original text was copied without attribution (including appropriate references to the original author(s) and/or paper titles) and without permission.
Due to the nature of this violation, reasonable effort should be made to remove all past references to this paper, and future references should be made to the following articles:
"Distribution and intensity of constraint in mammalian genomic sequence"
by Gregory M. Cooper, Eric A. Stone, George Asimenos, Eric D. Green, Serafim Batzoglou, and Arend Sidow
in Genome Research, Jul 2005; 15, pp 901 - 913, Cold Spring Harbor Press.
and
"Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes"
by Gregory M. Cooper, Michael Brudno, Eric D. Green, Serafim Batzoglou, and Arend Sidow
in Genome Research, May 2003; 13, pp 813 - 820, Cold Spring Harbor PressComparative sequence analyses on a collection of carefully chosen mammalian genomes could facilitate identification of functional elements within the human genome and allow quantification of evolutionary constraint at the single nucleotide level. High-resolution quantification would be informative for determining the distribution of important positions within functional elements and for evaluating the relative importance of nucleotide sites that carry single nucleotide polymorphisms (SNPs). The level of resolution in comparativ- sequence analyses is a direct function of sequence diversity, so the information content of a candidate mammalian genome can be defined as the sequence divergence it would add relative to already- sequenced genomes. Our study involves sequences from 29 mammals and we compute total neutral divergence present in set of mammals. Our results of how different mammals add to neutral divergence to the already fully sequenced mammals would increases the effectiveness of comparative genomics with mammalian scope.
Keywords :
biology computing; genetics; molecular biophysics; molecular configurations; polymorphism; comparative genomics; comparative sequence analyses; mammals; neutral divergence; nucleotide sites; sequence diversity; single nucleotide polymorphisms; Bioinformatics; Genetic mutations; Genomics; Information analysis; Notice of Violation; Organisms; Phylogeny; Sequences;