Development of a new arbitrary waveform defibrillator for cardiac electrophysiology research

Author

Triventi, Michele ; Mattei, Eugenio ; Delogu, Antonello ; Censi, Federica ; Calcagnini, Giovanni ; Bartolini, Pietro ; Aguel, Felipe ; Stohlman, Jayna ; Krauthamer, Victor

Author_Institution

Center for Device and Radiological Health, Food and Drug Administration, Silver Spring, MD, USA

fYear

2008

fDate

20-25 Aug. 2008

Firstpage

597

Lastpage

600

Abstract

The innovative arbitrary waveform defibrillator for animal research presented in this paper is based on two power linear amplifiers in bridge configuration. It is capable of delivering 10J shocks of arbitrary shape and duration. The system can be used to test new waveforms by comparing them to traditional ones, in in-vitro experiments. The system is battery operated, has an isolated output, and is PC controlled. Loads with impedance ranging from 10 to 25 ohms can be connected. A maximum of +/−130 V, 10A can be delivered to the loads. Effective voltage and current are measured and collected in the PC. Examples of waveforms as well as preliminary results from experiments of isolated rabbit hearts are presented.

Keywords

Animals; Batteries; Bridge circuits; Control systems; Electric shock; Impedance; In vitro; Power amplifiers; Shape; System testing; Animals; Defibrillators; Electronics, Medical; Electrophysiologic Techniques, Cardiac; Equipment Design; Equipment Failure Analysis; Reproducibility of Results; Research; Sensitivity and Specificity; Therapy, Computer-Assisted;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE

Conference_Location

Vancouver, BC

ISSN

1557-170X

Print_ISBN

978-1-4244-1814-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2008.4649223

Filename

4649223