• DocumentCode
    3066153
  • Title

    A pulse technique for control of fed-batch fermentations

  • Author

    Åkesson, Mats ; Hagander, Per ; Axelsson, Jan Peter

  • Author_Institution
    Dept. of Autom. Control, Lund Inst. of Technol., Sweden
  • fYear
    1997
  • fDate
    5-7 Oct 1997
  • Firstpage
    139
  • Lastpage
    144
  • Abstract
    A strategy for control of substrate feed rate in fed-batch fermentations is presented. The main idea is to make pulses in the feed rate and to evaluate the response in the dissolved oxygen signal. This gives an indirect measurement of the substrate demand that is used for feedback control of the feed rate. Experimental data is used to develop a model of a fermentation process. The model is used to derive simple tuning rules that require little process specific information. Several simulation experiments show the feasibility of the presented strategy
  • Keywords
    chemical technology; feedback; fermentation; pH control; process control; temperature control; three-term control; dissolved oxygen signal; fed-batch fermentations; indirect measurement; pulse technique; substrate demand; substrate feed rate; tuning rules; Automatic control; Chemical products; Feedback control; Feeds; Organisms; Pharmaceuticals; Production; Productivity; Pulse measurements; Sugar;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Control Applications, 1997., Proceedings of the 1997 IEEE International Conference on
  • Conference_Location
    Hartford, CT
  • Print_ISBN
    0-7803-3876-6
  • Type

    conf

  • DOI
    10.1109/CCA.1997.627517
  • Filename
    627517