Title :
SCDL Applications to Drug Discovery
Author :
Hecht, David A. ; Sheu, Phillip C Y ; Tsai, Jeffrey J P
Abstract :
Semantic Capability Description Language (SCDL) plays an important role as a common language and provides a generic format for problem formalization. In this paper we extend SCDL to include typical applications in drug discovery and development that include similarity and substructure searches, quantitative structure activity relationship modeling and in silico docking experiments.
Keywords :
bioinformatics; drugs; semantic Web; SCDL applications; drug discovery; in silico docking experiment; quantitative structure activity relationship model; semantic capability description language; Bioinformatics; Cells (biology); Chemistry; Computer science; Drugs; Pharmaceuticals; Productivity; Research and development; Systems biology; USA Councils; QSAR; Semantic Capability Description Language; docking; drug discovery; substructure and similarity searching;
Conference_Titel :
Bioinformatics and BioEngineering, 2009. BIBE '09. Ninth IEEE International Conference on
Conference_Location :
Taichung
Print_ISBN :
978-0-7695-3656-9
DOI :
10.1109/BIBE.2009.82
