Title :
Optical imaging of activation patterns in rabbit myocardium
Author :
Abbas, Rashida A. ; Lin, Shien-Fong ; Wikswo, John P., Jr.
Author_Institution :
Dept. of Phys. & Astron., Vanderbilt Univ., Nashville, TN, USA
Abstract :
The distribution of cardiac transmembrane potential during extracellular point stimulation reveals complex patterns of activation that cannot be explained by traditional cable theory. Simultaneous regions of depolarization and hyperpolarization exist surrounding the stimulating electrode. Epifluorescence images of cathodal stimulation in rabbit myocardium are presented here. Activation occurs from the site of depolarization called the virtual cathode
Keywords :
bioelectric potentials; biological techniques; biomembranes; cardiology; cellular biophysics; muscle; optical images; cardiac electrophysiology; cardiac transmembrane potential distribution; cathodal stimulation; depolarization; epifluorescence images; extracellular point stimulation; hyperpolarization; rabbit myocardium activation patterns; stimulating electrode; traditional cable theory; virtual cathode; Anodes; Cardiac tissue; Cathodes; Charge coupled devices; Electrodes; Extracellular; Myocardium; Optical imaging; Rabbits; Shape;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.575001
