Title :
Development of a magnetic Single Cell Micro Array
Author :
Liu, W. ; Dechev, N. ; Lee, S.-W. ; Foulds, I.G. ; Parameswaran, A. ; Burke, R. ; Park, E.J.
Author_Institution :
Department of Mechanical Engineering, University of Victoria, PO Box 3055 STN CSN, BC, Canada, V8W 3P6
Abstract :
Experiments using single cells are valuable for revealing individual cell behaviour, which is of interest to many biomedical researchers. In such experiments, various types of devices capable of aligning cells into organized arrays are often used. In this paper, we present a novel Single Cell Micro Array device that makes use of magnetic forces. Prototypes of this device have been fabricated, and successfully tested using Jurkat cells that have been labelled with nano-magnetic particles. Experimental results show that the prototypes are effective on capturing and placing the labelled cells in an array.
Keywords :
Automation; Cells (biology); Magnetic fields; Magnetic forces; Magnetic separation; Nanoscale devices; Prototypes; Testing; Throughput; Time factors; Algorithms; Alloys; Biocompatible Materials; Cells, Cultured; Computer Simulation; Equipment Design; Humans; Immunomagnetic Separation; Jurkat Cells; Magnetics; Microfluidic Analytical Techniques; Miniaturization; Particle Size; Software; Time Factors;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4649877