Title :
Development of flexible microelectrode arrays for recording cortical surface field potentials
Author :
Myllymaa, Sami ; Myllymaa, Katja ; Korhonen, Hannu ; Gureviciene, Irina ; Djupsund, Kaj ; Tanila, Heikki ; Lappalainen, Reijo
Author_Institution :
Department of Physics, University of Kuopio, Finland
Abstract :
The fabrication, characterization and application of an 8-channel flexible microelectrode array for recording cortical surface field potentials is described. Polyimide-based microelectrode arrays were fabricated by using photolithography and physical vapour deposition (PVD) methods. Polyimide was chosen as the substrate and insulation material due to its suitable mechanical properties and biocompatibility. Electrodes and transmission lines were formed by sputter-coating of platinum thin films. Microelectrode arrays were characterized and tested successfully in vitro by impedance spectroscopy and in vivo by somatosensory evoked potential (SEP) recordings in rats. These tests indicated good performance and the potential of microelectrode arrays.
Keywords :
Atherosclerosis; Biological materials; Chemical vapor deposition; Fabrication; Insulation; Lithography; Mechanical factors; Microelectrodes; Polyimides; Testing; Action Potentials; Algorithms; Animals; Cerebral Cortex; Electric Impedance; Electrodes; Electrophysiology; Evoked Potentials, Somatosensory; Materials Testing; Microelectrodes; Platinum; Rats; Spectrum Analysis; Stress, Mechanical; Titanium;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4649884
