Assessment of myocardial deformations from untagged cardiac cine MRI

This paper presents a method for the assessment of left ventricular myocardial deformations from untagged cardiac cine MRI. Firstly, a level set segmentation process is applied on the dataset to detect both endocardial and epicardial boundaries. Then the successive contours are matched using an original procedure that consists in an alignment followed by a morphing process. From the matched contours, we deduced an initial velocity of the contour points that will be used in a Thin-Plate Splines approximation method for estimating of the velocity flow on the complete myocardial structure. Finally, local measurements of ventricular deformations are derived from the velocity flow. The validation of the method is performed both mathematically and by comparing the measurements to those obtained on the same patients with the HARmonic Phase reference (HARP) method applied on matched tagged MR images.