Title :
Fluorescence imaging using transport-theory-based imaging operators
Author :
Chang, Jenghwa ; Graber, Harry ; Aronson, Raphael ; Barbour, Randall L.
Author_Institution :
Dept. of Pathol., SUNY Health Sci. Center, Brooklyn, NY, USA
Abstract :
We derive a linear operator, based on transport theory, for imaging fluorophore concentrations. The elements of the weight matrix of the resulting system are calculated from results of Monte Carlo simulations. Experimental data were collected by irradiating a cylindrical phantom containing two fluorophore-filled balloons with laser light. The reconstruction results show that good quality images can be obtained with both embedded objects accurately located
Keywords :
Monte Carlo methods; biomedical imaging; fluorescence; image reconstruction; laser applications in medicine; light propagation; medical image processing; optical tomography; CT-type scanning laser system; Monte Carlo simulations; cylindrical phantom; embedded objects; fluorescence imaging; fluorophore concentrations; fluorophore-filled balloons; good quality images; laser light; linear operator; optical imaging; physiological states; reconstruction results; transport-theory-based imaging operators; weight matrix elements; Detectors; Equations; Fluorescence; Image reconstruction; Imaging phantoms; Laser theory; Optical imaging; Optical propagation; Physiology; Probes;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.575227
