• DocumentCode
    3078258
  • Title

    Fractal dimension and wavelet decomposition for robust microarray data clustering

  • Author

    Istepanian, Robert S H ; Sungoor, Ala ; Nebel, Jean-Christophe

  • Author_Institution
    Mobile Information and Network Technologies Research Centre (MINT), Kingston University, London, KT1 2EE UK
  • fYear
    2008
  • fDate
    20-25 Aug. 2008
  • Firstpage
    4106
  • Lastpage
    4109
  • Abstract
    Microarrays are now established technologies which are considered as key to gene expression analysis. Their study is usually achieved by using clustering techniques. Genomic signal processing is a new area of research that combines genomics with digital signal processing methodologies. In this paper, we present a comparative analysis of two genomic signal processing methods for robust microarray data clustering. Techniques based on Fractal Dimension and Discrete Wavelet Decomposition with Vector Quantization are validated for standard data sets. Comparative analysis of the results indicates that these methods provide improved clustering accuracy compared to some conventional clustering techniques. Moreover, these classifiers don´t require any prior training procedures
  • Keywords
    Bioinformatics; Digital signal processing; Discrete wavelet transforms; Fractals; Gene expression; Genomics; Robustness; Signal analysis; Signal processing; Vector quantization; Algorithms; Cluster Analysis; Computers; Fractals; Genetic Vectors; Genome; Genomics; Humans; Models, Statistical; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Signal Processing, Computer-Assisted; Software;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
  • Conference_Location
    Vancouver, BC
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-1814-5
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2008.4650112
  • Filename
    4650112