DocumentCode
3078258
Title
Fractal dimension and wavelet decomposition for robust microarray data clustering
Author
Istepanian, Robert S H ; Sungoor, Ala ; Nebel, Jean-Christophe
Author_Institution
Mobile Information and Network Technologies Research Centre (MINT), Kingston University, London, KT1 2EE UK
fYear
2008
fDate
20-25 Aug. 2008
Firstpage
4106
Lastpage
4109
Abstract
Microarrays are now established technologies which are considered as key to gene expression analysis. Their study is usually achieved by using clustering techniques. Genomic signal processing is a new area of research that combines genomics with digital signal processing methodologies. In this paper, we present a comparative analysis of two genomic signal processing methods for robust microarray data clustering. Techniques based on Fractal Dimension and Discrete Wavelet Decomposition with Vector Quantization are validated for standard data sets. Comparative analysis of the results indicates that these methods provide improved clustering accuracy compared to some conventional clustering techniques. Moreover, these classifiers don´t require any prior training procedures
Keywords
Bioinformatics; Digital signal processing; Discrete wavelet transforms; Fractals; Gene expression; Genomics; Robustness; Signal analysis; Signal processing; Vector quantization; Algorithms; Cluster Analysis; Computers; Fractals; Genetic Vectors; Genome; Genomics; Humans; Models, Statistical; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Signal Processing, Computer-Assisted; Software;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location
Vancouver, BC
ISSN
1557-170X
Print_ISBN
978-1-4244-1814-5
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/IEMBS.2008.4650112
Filename
4650112
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