A novel optical multiplexed, label-free bio-photonic-sensor realized on CMOS-compatible optoelectronic integrated circuit (OEIC) platform

We present a novel label-free bio-photonic sensing system based on silicon opto-electric integrated circuit (OEIC) platform. The sensing system comprises an electrical-tracing assisted microring and a sensor microring integrating with an on-chip photodetector for direct electrical read-out. Multiplexing is achieved through an array of microrings and integrated photodetectors. Such sensing system circumvents the need of an expensive wavelength-tunable laser source by a low-cost broadband light source. This facilitates the development of a cost-effective point-of-care (POC) diagnostic tool. The completed system was demonstrated for label-free and multiplexed detection of DNA targets of pathogenic bacteria.