Title :
Physiological sensing through tissue with femto-second laser radiation
Author :
Parigger, Christian G. ; Johnson, Jacqueline A. ; Splinter, Robert
Author_Institution :
Center for Laser Applic., Univ. of Tennessee, Tullahoma, TN, USA
Abstract :
Application of femtosecond radiation for optical diagnostics through biological media offers opportunities for minimally invasive therapeutic applications. Interrogation of soft tissue behind hard tissue (e.g. bone) becomes feasible. The optical interaction for a femto second laser pulse is investigated with a hydroxyapatite fixture in representation of bone. Photo-acoustic spectroscopy is preferably applied for the identification and determination of location of optical anomalies in an otherwise homogeneous medium. Application of opto acoustic imaging presents an advantageous mechanism-of-action for imaging through, for instance bone, specifically applied to brain tumors. Furthermore, increase in irradiance levels allows us to use femto second laser radiation for therapy.
Keywords :
biomedical optical imaging; high-speed optical techniques; laser applications in medicine; photoacoustic spectroscopy; radiation therapy; tumours; biological media; biological tissue; brain tumor; femtosecond laser radiation therapy; hard tissue; hydroxyapatite fixture; minimally invasive therapeutic application; optical diagnostics; opto acoustic imaging; photo-acoustic spectroscopy; physiological sensing; soft tissue; Biomedical optical imaging; Image resolution; Iron; Particle beam optics; Size measurement; Ultrafast optics; Volume measurement;
Conference_Titel :
High Capacity Optical Networks and Enabling Technologies (HONET), 2012 9th International Conference on
Conference_Location :
Istanbul
Print_ISBN :
978-1-4673-2891-3
DOI :
10.1109/HONET.2012.6421463