Title :
Cardiac nonmyocyte hyperplasia is modulated by angiotensin II and stretch
Author :
Cezeaux, Judy L. ; Banta, Kristye S. ; Jacobs, William R.
Author_Institution :
Dept. of Mech. & Aerosp. Eng. & Eng. Sci., Tennessee Univ., Knoxville, TN, USA
Abstract :
Results indicate that angiotensin II and stretch are necessary for the initiation of the hyperplasia response of nonmyocytes in cardiac hypertrophy. Because renin message levels determined using RT-PCR were quite low, however, it is unlikely that an autocrine mechanism of angiotensin production using renin is present in nonmyocytes
Keywords :
biomechanics; cardiology; cellular biophysics; proteins; angiotensin II; cardiac hypertrophy; cardiac nonmyocyte hyperplasia; cardiovascular disease; heart cell biomechanics; pressure overload hypertrophy; stretch; Aerospace engineering; Biomedical engineering; Biomembranes; DNA; Jacobian matrices; Plasma measurements; Polymers; Production; Proteins; Road transportation;
Conference_Titel :
Biomedical Engineering Conference, 1997., Proceedings of the 1997 Sixteenth Southern
Conference_Location :
Biloxi, MS
Print_ISBN :
0-7803-3869-3
DOI :
10.1109/SBEC.1997.583214
