Title :
Osteoblast cell response to hydroxyapatite of different heat treatments
Author :
Ong, JL ; Cavin, R.
Author_Institution :
Dept. of Restorative Dentistry, Univ. of Texas Health Sci. Center, San Antonio, TX, USA
Abstract :
In vitro osteoblast precursor cell responses to characterized hydroxyapatite (HA) surfaces of different treatments were investigated. The sintered HA samples were observed to have the highest crystallite size compared to the as-received HA and calcined HA samples. As indicated by increased alkaline phosphatase specific activity and 1,25 (OH2) vitamin D3 stimulated osteocalcin production, a more differentiated osteoblast-like phenotype was observed on the sintered HA surfaces compared to the as-received HA and calcined HA surfaces
Keywords :
bone; cellular biophysics; heat treatment; prosthetics; 1,25 (OH2) vitamin D3 stimulated osteocalcin production; alkaline phosphatase specific activity; biomedical material; calcined samples; crystallite size; hydroxyapatite; osteoblast cell response; Analysis of variance; Bones; Crystallization; Heat treatment; Plasma properties; Production; Scanning electron microscopy; Surface treatment; Testing; Thermal spraying;
Conference_Titel :
Biomedical Engineering Conference, 1997., Proceedings of the 1997 Sixteenth Southern
Conference_Location :
Biloxi, MS
Print_ISBN :
0-7803-3869-3
DOI :
10.1109/SBEC.1997.583246