Title :
Kinetic Study of Calcium Phosphate Cement Containing Chitosan in Its Liquid Phase
Author :
Liu, Hua ; Tan, Ying
Author_Institution :
Coll. of Mater. Sci. & Eng., South China Univ. of Technol., Guangzhou, China
Abstract :
In this study, the kinetic mecha-nisms for the hydration process of calcium phosphate cement (CPC) containing chitosan in its liquid phase were investigated by X-ray diffraction quantitative analysis. The powder component consisted of an equimolar mixture of tetracalcium phosphate and dicalcium phosphate anhydrous. The liquid component consisted of chitosan (3 wt%), citric acid (5 wt%) and glucose (15 wt%) solution. The results show that the hardening process of CPC is initially controlled by the dissolution of reactants in a 2-h period and subsequently by diffusion through the product layer of hydroxyapatite (HA) around the grains. The compressive strength rises approximately linearly with the increase of the extent of conversion in a 2-h period, and a maximum compressive strength of 30.2±±0.8 MPa is obtained in 2 hours. Then the compressive strength drops a little with an increase in the extent of conversion. The final product of setting reaction is acicular HA crystal.
Keywords :
X-ray diffraction; bioceramics; calcium compounds; chemical analysis; compressive strength; dissolving; solvation; Ca4(PO4)2O; X-ray diffraction; calcium phosphate cement; chitosan; compressive strength; dissolution; equimolar mixture; hydration process; hydroxyapatite; liquid phase; quantitative analysis; Calcium; Glass; Kinetic theory; Materials science and technology; Powders; Scanning electron microscopy; Solids; Sugar; Thermodynamics; X-ray diffraction;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5515310