Biological Oxidation Resistance of L-Ascorbic Acid Cellulose Ester

L-ascorbic acid and sodium carboxymethylcellulose were taken as raw material to synthesize polymer material L-ascorbic acid cellulose ester which had antioxidation effect. Antioxidation effect of o benzylgalloyl microcrystalline cellulose ester was appraised in vitro. The results showed that all the different concentrations L-ascorbic acid cellulose ester significantly improved GSH-Px activity of mice liver. But there was no significant difference among the low dose, middle dose and high dose group. Consequently, it can not explain that there was dose-effect relationship between them. L-ascorbic acid cellulose ester could significantly inhibit generation of lipid peroxidation product malondialdehyde(MDA) and oxidative hemolysis of erythrocyte, and there was very significantly dose-response relationship between them. It can provide technical foundation for the further study on anti-oxidative new functional polymer materials.