Title :
Spectral Clustering and Feature Selection for Microarray Data
Author :
Garcia-Garcia, Daniel ; Santos-Rodriguez, R.
Author_Institution :
Dept. of Signal Theor. & Commun., Univ. Carlos III de Madrid, Leganes, Spain
Abstract :
Microarray datasets comprise a large number of gene expression values and a relatively small number of samples. Feature selection algorithms are very useful in these situations in order to find a compact subset of informative features. We propose a redundancy control method for algorithms in the recently proposed SPEC family of spectral-based feature selection algorithms. This method is applied to find relevant genes in order to cluster samples corresponding to three kinds of cancer: lung, breast and colon.
Keywords :
cancer; feature extraction; genetics; medical computing; pattern clustering; redundancy; breast cancer; colon cancer; feature selection algorithms; gene expression; lung cancer; microarray datasets; redundancy control method; spectral clustering; Cancer; Clustering algorithms; Gene expression; Graph theory; Humans; Laplace equations; Lungs; Machine learning; Machine learning algorithms; Mutual information; bioinformatics; cancer; feature selection; microarray data; spectral clustering;
Conference_Titel :
Machine Learning and Applications, 2009. ICMLA '09. International Conference on
Conference_Location :
Miami Beach, FL
Print_ISBN :
978-0-7695-3926-3
DOI :
10.1109/ICMLA.2009.86