Title :
Detection of Lung Cancer with Phase-Contrast X-ray Imaging Using Synchrotron Radiation
Author :
Liu, Ping ; Sun, Jianqi ; Guan, Yijing ; Zhang, Guilin ; Xu, Lisa Xuemin
Author_Institution :
Sch. of Life Sci. & Technol., Shanghai Jiao Tong Univ.
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
In the present study, the feasibility of applying synchrotron radiation for the detection of lung cancers was investigated. Lung cancer tissues grown in mice over different periods were observed with phase-contrast synchrotron X-ray chest imaging. Irregular and tortuous vessels appearing in early cancer angiogenesis were found in the periphery region of the implanted cancer. Structure difference was clearly shown between normal tissue and early stage solid cancer in micrometers. Results from this study indicate that synchrotron X-ray may open broad perspectives for imaging cancer development and progression noninvasively
Keywords :
cancer; diagnostic radiography; lung; synchrotron radiation; tumours; angiogenesis; chest imaging; lung cancer tissue detection; mice; phase-contrast X-ray imaging; synchrotron radiation; tortuous vessel; Cancer detection; Lungs; Mice; Optical imaging; Phase detection; Radiation detectors; Synchrotron radiation; X-ray detection; X-ray detectors; X-ray imaging;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260802
