DocumentCode
3118321
Title
Genomic signature: the mathematical functions associated with it
Author
De Giacomo, N. ; de Santis, F.
Author_Institution
Dept. of Informatica e Applicazioni R.M. Capocelli, Univ. of Salerno, Baronissi, Italy
fYear
2002
fDate
2002
Firstpage
102
Lastpage
103
Abstract
Extensive data analyses support the proposal that each living organism possess a genomic signature consisting of oligonucleotide relative abundance values calculated from genomic sequences. The Chaos Game Representation shows that the core features characterizing the whole genome are preserved in short subsequences of it, validating the idea of a genomic signature. This paper present an alternative approach to the genomic signature detection. Although ensuring the same information retrieved from classical methods, it presents the advantage to be conceptually very simple and computationally less expensive.
Keywords
chaos; genetics; interpolation; physiological models; polynomials; Chaos Game Representation; computationally less expensive; conceptually very simple; core features; genomic signature; living organism; mathematical functions; whole genome characterization; Bioinformatics; Chaos; DNA; Data analysis; Frequency estimation; Frequency measurement; Genetics; Genomics; Organisms; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN
0-7803-7557-2
Type
conf
DOI
10.1109/MCTE.2002.1175025
Filename
1175025
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