DocumentCode
3118599
Title
A wavelet based method to predict the alpha helix content in the secondary structure of globular proteins
Author
Pattini, L. ; Riva, L. ; Cerutti, S.
Author_Institution
Dept. of Biomed. Eng., Polytech. Univ., Milan, Italy
fYear
2002
fDate
2002
Firstpage
132
Lastpage
133
Abstract
A single sequence based method is proposed to predict the α-helix content of a protein from its primary sequence. The analysis of the secondary structure of the protein is performed using the information derived from its hydrophobicity profile and the amino acid composition. The method is applied to a test set of 347 proteins obtaining a residue by residue accuracy of 72%.
Keywords
molecular biophysics; molecular configurations; proteins; wavelet transforms; α-helix content; alpha helix content prediction; amino acid composition; globular proteins secondary structure; hydrophobicity profile; primary sequence physical characteristics; protein final folding; residue by residue accuracy; secondary structure; wavelet based method; Amino acids; Biomedical engineering; Databases; Information analysis; Peptides; Performance analysis; Protein engineering; Sequences; Signal processing; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN
0-7803-7557-2
Type
conf
DOI
10.1109/MCTE.2002.1175039
Filename
1175039
Link To Document