Microscopical characterization of nanocapsules templated on ionic crystals and biological cells towards bio-medical applications

Author

Diaspro, A. ; Krol, S. ; Cavalleri, O. ; Silvano, D. ; Gliozzi, A.

Author_Institution

Dept. of Phys., Genoa Univ., Genova, Italy

fYear

2002

fDate

2002

Firstpage

147

Lastpage

148

Abstract

Nanocapsules represent a comparatively new class of colloids with controlled nanostructure. The use of crystals as core influences the wall texture and the properties of the capsules. Yeast cells constitute a candidate as core. They are a good system for testing the protective ability of shells and the permeability of the walls with respect to the needs of biological systems, namely: feeding and stability against attacks. The main features of the nanocapsules have been studied by two-photon, confocal and atomic force microscopy. Nanocapsules are of bio-medical interest since they can be used, for example, for the controlled release and targeting of drugs as well as for the protection of enzymes, proteins and foreign cells.

Keywords

biomedical materials; cellular biophysics; colloids; crystals; drug delivery systems; nanostructured materials; permeability; polymer electrolytes; atomic force microscopy; biological cells; biomedical applications; capsules properties; confocal microscopy; controlled drug release; drugs targeting; enzymes protection; foreign cells; ionic crystals; microscopical characterization; proteins; two-photon microscopy; wall texture; yeast cells; Atomic force microscopy; Biological cells; Biological systems; Colloidal crystals; Fungi; Nanobioscience; Permeability; Protection; Stability; System testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on

Print_ISBN

0-7803-7557-2

Type

conf

DOI

10.1109/MCTE.2002.1175047

Filename

1175047