Title :
A free-standing hydrostatic bioreactor for neural tissue culture
Author :
Previti, A. ; Vozzi, G. ; Scarpa, C. ; Novelli, E. ; Resta, V. ; Galli-Resta, L. ; Vivaldi, F. ; Ahluwalia, A.
Author_Institution :
Centro Interdepartimentale di Ricerca "E. Piaggio", Italy
Abstract :
A hydrostatic bioreactor for the study of cells and tissue is described. The system, which was developed to determine the effects of increased pressure on neural tissue, is capable of applying pressures of up to 100 mmHg with an error of ±2 mmHg in an enclosed chamber. On-line pH, pressure and temperature control enables the system to be monitored continuously and to be independent of bulky cell culture incubators.
Keywords :
biocontrol; biological techniques; biological tissues; cellular biophysics; neurophysiology; pressure control; temperature control; 100 mmHg; astronauts; bulky cell culture incubators; cerebral tissue; dynamic environments; elevated intracranial pressure; elevated intraocular pressure; enclosed chamber; free-standing hydrostatic bioreactor; increased pressure effects; neural tissue culture; on-line pH control; patients with cerebral edema; patients with glaucoma; physiological conditions simulation; retinal tissue; space missions; Bioreactors; Cells (biology); Control systems; Neurophysiology; Physiology; Pressure control; Regulators; Temperature control; Valves; Water heating;
Conference_Titel :
Molecular, Cellular and Tissue Engineering, 2002. Proceedings of the IEEE-EMBS Special Topic Conference on
Print_ISBN :
0-7803-7557-2
DOI :
10.1109/MCTE.2002.1175050
