Title :
XOA: Web-Enabled Cross-Ontological Analytics
Author :
Riensche, Roderick M. ; Baddeley, Bob L. ; Sanfilippo, Antonio P. ; Posse, Christian ; Gopalan, Banu
Author_Institution :
Pacific Northwest Nat. Lab., Richland
Abstract :
We describe the development of the cross-ontological analytics (XOA) system, which implements a novel Web-enabled approach for computing similarities across gene and gene products with associated specifications of functional genomic relationships. The XOA system enables biologists to leverage combinations of hierarchical and associative data across multiple subontologies in order to reveal relationships between gene and gene products that might not otherwise be exposed by existing methods of computational analysis. We also provide examples of specific proof-of-concept applications in which XOA has been successfully tested.
Keywords :
Internet; associative processing; biology computing; genetic engineering; ontologies (artificial intelligence); Web-enabled approach; XOA; cross-ontological analytics system; functional genomic relationship; gene products; proof-of-concept; Bioinformatics; Biological information theory; Biological processes; Biology computing; Databases; Genomics; Laboratories; Ontologies; Taste buds; Testing;
Conference_Titel :
Services, 2007 IEEE Congress on
Conference_Location :
Salt Lake City, UT
Print_ISBN :
978-0-7695-2926-4
DOI :
10.1109/SERVICES.2007.73
