XOA: Web-Enabled Cross-Ontological Analytics

Author

Riensche, Roderick M. ; Baddeley, Bob L. ; Sanfilippo, Antonio P. ; Posse, Christian ; Gopalan, Banu

Author_Institution

Pacific Northwest Nat. Lab., Richland

fYear

2007

fDate

9-13 July 2007

Firstpage

99

Lastpage

105

Abstract

We describe the development of the cross-ontological analytics (XOA) system, which implements a novel Web-enabled approach for computing similarities across gene and gene products with associated specifications of functional genomic relationships. The XOA system enables biologists to leverage combinations of hierarchical and associative data across multiple subontologies in order to reveal relationships between gene and gene products that might not otherwise be exposed by existing methods of computational analysis. We also provide examples of specific proof-of-concept applications in which XOA has been successfully tested.

Keywords

Internet; associative processing; biology computing; genetic engineering; ontologies (artificial intelligence); Web-enabled approach; XOA; cross-ontological analytics system; functional genomic relationship; gene products; proof-of-concept; Bioinformatics; Biological information theory; Biological processes; Biology computing; Databases; Genomics; Laboratories; Ontologies; Taste buds; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Services, 2007 IEEE Congress on

Conference_Location

Salt Lake City, UT

Print_ISBN

978-0-7695-2926-4

Type

conf

DOI

10.1109/SERVICES.2007.73

Filename

4278784