DocumentCode :
3120904
Title :
Synthesis of Novel Glycyrrhetinic Acid Analogues
Author :
Meng, Yan-Qiu ; Wang, Xiang-Lei ; Song, Yan-Ling ; Li, Feng-Qing
Author_Institution :
Dept. of Pharm. Eng., Shenyang Univ. of Chem. Technol., Shenyang, China
fYear :
2010
fDate :
18-20 June 2010
Firstpage :
1
Lastpage :
4
Abstract :
Glycyrrhetinic acid (GA, 3 β-hydroxyl-11-oxo-olean-12-ene-29-oic acid, 1) isolated from Glycyrrhiza glabra was found to have several pharmacological activities. A series of novel GA derivatives were designed and synthesized as antitumor agents. Their structures were confirmed using MS and 1H-NMR.
Keywords :
biomedical NMR; botany; cancer; drugs; molecular biophysics; tumours; 1H-NMR; GA derivatives; Glycyrrhiza glabra; MS; antitumor agents; glycyrrhetinic acid analogues; pharmacological activities; Cancer; Cells (biology); Chemical technology; Clouds; Design engineering; Electrons; Petroleum; Pharmaceuticals; Protons; Temperature;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
ISSN :
2151-7614
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
Type :
conf
DOI :
10.1109/ICBBE.2010.5516432
Filename :
5516432
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=3120904
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