DocumentCode
3121668
Title
Synthesis of Novel Ursolic Acid Derivatives
Author
Meng, Yan-Qiu ; Xia, Yan ; Yan, Zhao-Kai ; Li, Yun-Yun ; Song, Yan-Ling
Author_Institution
Dept. of Pharm. Eng., Shenyang Univ. of Chem. Technol., Shenyang, China
fYear
2010
fDate
18-20 June 2010
Firstpage
1
Lastpage
4
Abstract
To investigate anti-tumor structure-activity relation- ship of derivatives of ursolic acid and obtain more effective anti-tumor compounds, 12 ursolic acid derivatives (10 novel compounds) with modified structures at the C-3 and C-28 position were synthesized. The structures of all compounds were confirmed by ESI-MS, IR and 1H-NMR spectral date.
Keywords
nuclear magnetic resonance; pharmaceutical technology; tumours; ESI-MS; H-NMR; IR spectral date; anti-tumor structure-activity relationship; ursolic acid derivatives; ursolic acid synthesis; Chemical technology; Design engineering; Humans; Immune system; Neoplasms; Pharmaceuticals; Powders; Power engineering and energy; Protons; Silicon compounds;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location
Chengdu
ISSN
2151-7614
Print_ISBN
978-1-4244-4712-1
Electronic_ISBN
2151-7614
Type
conf
DOI
10.1109/ICBBE.2010.5516467
Filename
5516467
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