Experimental Study on the Interaction of QDs with BSA

Author

Liu, Kun ; Liu, Qinghua ; Xiao, Hua ; Xiong, Jianwen

Author_Institution

Sch. of Phys. & Telecommun. Eng., South China Normal Univ., Guangzhou, China

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

4

Abstract

The study of the interaction and the mechanism of the interaction of semiconductor quantum dots (QDs) with BSA by fluorescence spectrum. The results showed that BSA occurred static quenching within increasing concentration of QDs, the fluorescence intensity of the QDs gradually enhanced with increasing the concentration of BSA, which is because of formation of core-shell structure. The results will provide an reference for QDs toxicology in biology and medicine and the safety of treating cancer with Photodynamic Therapy (PDT).

Keywords

bio-optics; biomedical materials; fluorescence; molecular biophysics; nanobiotechnology; proteins; radiation quenching; semiconductor quantum dots; BSA; bovine serum albumin; cancer; core-shell structure; fluorescence spectrum; photodynamic therapy; semiconductor quantum dots; static quenching; toxicology; Absorption; Buffer storage; Fluorescence; Medical treatment; Nanobioscience; Optical buffering; Physics; Quantum dots; Safety; Toxicology;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5516624

Filename

5516624