Title :
Multispectral Fluorescence Imaging for Tumor Detection and Molecular Biology
Author :
Svensson, Jenny ; Axelsson, Johan ; Johansson, Ann ; Bendsoe, Niels ; Svanberg, Katarina ; Andersson-Engels, Stefan
Author_Institution :
Dept. of Phys., Lund Inst. of Technol.
Abstract :
The use of a multispectral imaging system provides possibilities to map all information encoded in the spectral fingerprint of an exogenous or endogenous chromophore in biological media. The spectral information has been used to demarcate the spatial extent of superficial skin tumours. Monitoring the fluorescence emitted from the photosensitizer over time yield information about the photodynamic treatment progression. The multispectral approach will also enable depth estimation of a lesion and thus allow quantitative measurements of a fluorophore as shown by the results presented
Keywords :
biomedical measurement; biomedical optical imaging; cancer; fluorescence; molecular biophysics; photochemistry; skin; tumours; endogenous chromophore; exogenous chromophore; fluorophore; lesion depth estimation; molecular biology; multispectral fluorescence imaging system; photosensitizer; quantitative measurement; spectral fingerprints; spectral information encoding; superficial skin tumor detection; Biomedical optical imaging; Fluorescence; Hospitals; Lesions; Multispectral imaging; Optical imaging; Optical scattering; Skin; Tomography; Tumors;
Conference_Titel :
Lasers and Electro-Optics Society, 2006. LEOS 2006. 19th Annual Meeting of the IEEE
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-9555-7
Electronic_ISBN :
0-7803-9555-7
DOI :
10.1109/LEOS.2006.278993
