Title :
Capping-ligands-induced synthesis of non-spherical magnetite nanoparticles for hyperthermia and their biocompatibility study
Author :
Li, L. ; Leung, C. ; Du, Y. ; Wong, C. ; Pong, P.
Author_Institution :
Dept. of Electr. & Electron. Eng., Univ. of Hong Kong, Hong Kong, China
Abstract :
This study aims to use different kinds of capping ligands (oleic acid, oleylamine, 1,2-tetradecanediol, decanoic acid, and lauric acid) for synthesis by thermal decomposition and to adjust the morphology of magnetite nanoparticles into non-spherical shape. The nanoparticle products are characterized using TEM, EDX, electron diffraction, SEM, and VSM. The synthesized nanoparticles show typical superparamagnetic behavior with a saturation magnetization value of 54 emu/g. A comparative cytotoxicity study is performed on human hepatoma cell lines and immortalized normal human liver cell lines to investigate biocompatibility of nanoparticles for hyperthermia application.
Keywords :
X-ray chemical analysis; biomedical materials; cellular biophysics; electron diffraction; hyperthermia; iron compounds; liver; magnetic particles; magnetisation; magnetometry; nanofabrication; nanomagnetics; nanomedicine; nanoparticles; pyrolysis; scanning electron microscopy; superparamagnetism; transmission electron microscopy; 1,2-tetradecanediol; EDX; Fe3O4; SEM; TEM; VSM; biocompatibility; capping-ligands-induced synthesis; cytotoxicity; decanoic acid; electron diffraction; human hepatoma cell lines; hyperthermia; immortalized normal human liver cell lines; lauric acid; nonspherical magnetite nanoparticles; oleic acid; oleylamine; saturation magnetization; superparamagnetism; thermal decomposition; Iron; Magnetic resonance imaging; Morphology; Nanoparticles; Perpendicular magnetic anisotropy; Saturation magnetization;
Conference_Titel :
Magnetics Conference (INTERMAG), 2015 IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4799-7321-7
DOI :
10.1109/INTMAG.2015.7157201
