DocumentCode
3138836
Title
Nanofabrication for cell engineering
Author
Wilkinson, C.D.W. ; Casey, B.G. ; Curtis, A.S.G.
Author_Institution
Dept. of Electron. & Electr. Eng., Glasgow Univ., UK
fYear
1997
fDate
35718
Firstpage
42522
Lastpage
42524
Abstract
In the engineering of tissue for use in prostheses, it is often desirable to ensure that the cells during re-growth are oriented in the same direction as in the intact tissue or organ. Nerve cells need to follow a route from the sensory end to the central nervous system, tendon cells for maximum strength need to be aligned to the axis of the tendon and so on. The authors discuss a progression of experiments which have been carried out to investigate the effects of micron-sized grooves on orientating and guiding cells in culture
Keywords
nanotechnology; broken tendons; cell engineering; cell guiding; cell orientation; culture; dies use; electron beam resist; grooved polymeric membrane; mechanical transfer methods; micron-sized grooves; nanofabrication; nerve cells; prostheses; re-growth promotion; replication; tendon cells; tissue engineering;
fLanguage
English
Publisher
iet
Conference_Titel
Microsensors in Medicine (Ref. No: 1997/318), IEE Colloquium on
Conference_Location
London
Type
conf
DOI
10.1049/ic:19971062
Filename
660633
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