Title :
Nanofabrication for cell engineering
Author :
Wilkinson, C.D.W. ; Casey, B.G. ; Curtis, A.S.G.
Author_Institution :
Dept. of Electron. & Electr. Eng., Glasgow Univ., UK
Abstract :
In the engineering of tissue for use in prostheses, it is often desirable to ensure that the cells during re-growth are oriented in the same direction as in the intact tissue or organ. Nerve cells need to follow a route from the sensory end to the central nervous system, tendon cells for maximum strength need to be aligned to the axis of the tendon and so on. The authors discuss a progression of experiments which have been carried out to investigate the effects of micron-sized grooves on orientating and guiding cells in culture
Keywords :
nanotechnology; broken tendons; cell engineering; cell guiding; cell orientation; culture; dies use; electron beam resist; grooved polymeric membrane; mechanical transfer methods; micron-sized grooves; nanofabrication; nerve cells; prostheses; re-growth promotion; replication; tendon cells; tissue engineering;
Conference_Titel :
Microsensors in Medicine (Ref. No: 1997/318), IEE Colloquium on
Conference_Location :
London
DOI :
10.1049/ic:19971062
