Title :
Genome-Wide Identification of Orthologs of miR-1302 Genes in Placental Mammals
Author :
Yuan, Zhidong ; Sun, Xiao
Author_Institution :
State Key Lab. of Bioelectronics, Southeast Univ., Nanjing, China
Abstract :
MicroRNAs (miRNAs) are small noncoding RNAs which regulate gene expression. In this research, we used the Multiz alignments data of 44 Vertebrates to retrieve syntenic homolog sequences. And we identified 37 members of miR-1302 family among 71 potential homolog sequences. Then we analyzed the 37 homologs of hsa-mir-1302s by RepeatMasker and found all of these sequences are derived from MER53 elements. Also we show our method is a good way to acquire the orthologs.
Keywords :
biological techniques; cellular biophysics; genetics; genomics; molecular biophysics; molecular configurations; MER53 elements; Multiz alignment data; RepeatMasker; gene expression; genome-wide identification; hsa-mir-1302s; miR-1302 family; miR-1302 genes; microRNAs; noncoding RNAs; placental mammals; syntenic homolog sequences; vertebrates; Bioinformatics; Biomedical engineering; Engineering in medicine and biology; Gene expression; Genomics; Horses; Humans; Laboratories; RNA; Sequences;
Conference_Titel :
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-4712-1
Electronic_ISBN :
2151-7614
DOI :
10.1109/ICBBE.2010.5517434
