Title :
Microfluidic sub-millisecond mixers for the study of chemical reaction kinetics
Author :
Desai, Amish ; Bökenkamp, Dirk ; Yang, Xing ; Tai, Yu-Chong ; Marzluff, Elaine ; Mayo, Stephen
Author_Institution :
Dept. of Electr. Eng., California Inst. of Technol., Pasadena, CA, USA
Abstract :
We present a micromachined, high Reynolds number (2000-6000), sub-millisecond liquid mixer for the study of chemical reaction kinetics. This 1 cm×1 cm×1 mm bulk micromachined silicon mixer is capable of initiating and quenching (starting and stopping) chemical reactions in intervals as short as 100 μs. The centimeter sized mixer chip contains two tee mixers connected by one channel which serves as a reaction chamber. Each tee mixer consists of opposing channels where liquids meet head-on and exit into a third channel forming the base of a “T”. Our mixer performance was characterized by employing two carefully chosen chemical reactions with reaction time constants of 3 ms and 9 ms along with visualization techniques using dyes and acid-base indicators
Keywords :
biological techniques; channel flow; chemically reactive flow; flow visualisation; micromachining; mixing; reaction kinetics; reaction rate constants; silicon; turbulence; 1 cm; 1 mm; 100 mus; 3 ms; 9 ms; acid-base indicators; biochemical processes; bulk micromachined silicon mixer; centimeter sized mixer chip; chemical reaction initiation; chemical reaction kinetics; chemical reaction quenching; dyes; microfluidic sub-millisecond mixers; micromachined high Reynolds number sub-millisecond liquid mixer; one channel; reaction chamber; reaction time constants; tee mixers; visualization techniques; Biochemistry; Biology; Chemical analysis; Chemical engineering; Delay effects; Kinetic theory; Liquids; Microfluidics; Micromechanical devices; Silicon;
Conference_Titel :
Solid State Sensors and Actuators, 1997. TRANSDUCERS '97 Chicago., 1997 International Conference on
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-3829-4
DOI :
10.1109/SENSOR.1997.613609
