Title :
Probing and using the dielectric properties of microtubules within microsystems integrating Indium-Tin oxide microelectrodes
Author :
Morin, F.O. ; Tarhan, M.C. ; Fujita, Hideaki
Author_Institution :
LIMMS/CNRS-IIS, Tokyo
Abstract :
The present paper describes the use of indium-tin oxide microelectrodes for manipulating microtubules in solution through interaction with electric fields. The experimental set-up that is described here is a platform for both investigating the fundamental dielectric properties of microtubules and developing methods to exert control over their behaviour in solution. Direct applications of such methods can be found in the development of microsystems integrating nano-machines based on motor proteins such as kinesin or dynein. Electro-rotation of microtubules in solution is presented as an example of interaction between microtubules and electric field
Keywords :
bioMEMS; bioelectric phenomena; biological techniques; cellular transport; etching; indium compounds; microelectrodes; micromechanical devices; molecular biophysics; proteins; ITO; InSnO; dry etching; dynein; electric field interaction; electro-rotation; indium-tin oxide microelectrodes; kinesin; microsystems; microtubule dielectric properties; microtubule manipulation; microtubule probes; motor proteins; nano-machines; Aluminum; Dielectrics; Dry etching; Indium tin oxide; Microelectrodes; Microscopy; Nanobioscience; Polymers; Proteins; Stability; Dry Etching of Indium-Tin Oxide; Electro-rotation; Microelectrodes; Microtubules;
Conference_Titel :
Microtechnologies in Medicine and Biology, 2006 International Conference on
Conference_Location :
Okinawa
Print_ISBN :
1-4244-0338-3
Electronic_ISBN :
1-4244-0338-3
DOI :
10.1109/MMB.2006.251489