Ultra Giant Vesicles out of a Planar Membrane

Author

Funakoshi, Kei ; Suzuki, Hiroaki ; Takeuchi, Shoji

Author_Institution

Inst. of Ind. Sci., Tokyo Univ.

fYear

2006

fDate

9-12 May 2006

Firstpage

68

Lastpage

69

Abstract

We report a method for forming ultra giant lipid vesicles. A chip device with a micro-jet nozzle was fabricated. The vesicles were produced by applying pulsed micro jets to a planar lipid bilayer, analogous to blowing soap bubbles from a liquid film. Using this method, lipid vesicles with diameters of about 500 mum were formed one-by-one. This method enables the encapsulation of target molecules or nano particles into the vesicles rapidly and efficiently

Keywords

biological techniques; biomembranes; cellular biophysics; jets; lab-on-a-chip; lipid bilayers; microfluidics; nozzles; artificial biofunctional membranes; chip device; lab on a chip; microcapsule; microjet nozzle; nano particle encapsulation; planar lipid bilayer; planar membrane; pulsed micro jets; target molecule encapsulation; ultra giant lipid vesicles formation; Biology; Biomembranes; Cells (biology); Drug delivery; Encapsulation; Fractionation; Glass; Lipidomics; Microfluidics; Substrates; Artificial biofunctional membranes; Lab on a chip; Micro capsule; Microjet device;

fLanguage

English

Publisher

ieee

Conference_Titel

Microtechnologies in Medicine and Biology, 2006 International Conference on

Conference_Location

Okinawa

Print_ISBN

1-4244-0338-3

Electronic_ISBN

1-4244-0338-3

Type

conf

DOI

10.1109/MMB.2006.251492

Filename

4281310