Topographic Elasticity Measurement for an Estimation of Hepatic Fibrosis Using Tactile Mapping System

Author

Murayama, Y. ; Yajima, T. ; Kuda, Fu ; Suzuki, S. ; Hatakeyama, Y. ; Sakuma, H. ; Takenoshita, S. ; Constantinou, Christos E. ; Omata, S.

Author_Institution

NEWCAT Inst., Nihon Univ.

fYear

2006

fDate

9-12 May 2006

Firstpage

295

Lastpage

296

Abstract

In this study, a tactile mapping system was developed to obtain a two-dimensional elasticity distribution image in order to study the cause of hardening of a chronic hepatitis and liver cirrhosis. Tactile Mapping system utilized a micro tactile sensor which can measure a local elasticity of a very thin sample in micron scale. By comparing the tactile mapping image and azan stained image, it was indicated that the accumulation of the collagen might be the main cause of the liver hardening

Keywords

biochemistry; biological tissues; biomechanics; biomedical optical imaging; elasticity; liver; microsensors; molecular biophysics; optical microscopy; proteins; tactile sensors; azan stained image; chronic hepatitis; collagen accumulation; hepatic fibrosis estimation; liver cirrhosis; liver hardening; micro tactile sensor; stereoscopic microscope image; tactile mapping image system; topographic elasticity measurement; two-dimensional elasticity distribution; Biomedical imaging; Elasticity; Frequency measurement; Linearity; Liver diseases; Performance evaluation; Resonance; Resonant frequency; Tactile sensors; Vibration measurement; Azan stain; Elasticity; Liver cirrhosis; Micro Tactile Sensor; Tactile Mapping;

fLanguage

English

Publisher

ieee

Conference_Titel

Microtechnologies in Medicine and Biology, 2006 International Conference on

Conference_Location

Okinawa

Print_ISBN

1-4244-0338-3

Electronic_ISBN

1-4244-0338-3

Type

conf

DOI

10.1109/MMB.2006.251554

Filename

4281372