Title :
Study of the structure and the molecular mobility of a new biological matrix (collagen/peptides)
Author :
Tintar, D. ; Samouillan, V. ; Dandurand, J. ; Lacabanne, C. ; Spina, M. ; Naso, F. ; Gandaglia, A. ; Danesin, R. ; Dettin, M.
Author_Institution :
Lab. de Phys. des Polymeres, Univ. Paul Sabatier, Toulouse
Abstract :
The thermal analyses have showed a slight decreasing of the denaturation temperature for all the treated collagens. These results suggest a slight destabilization of treatments on the collagen triple helix. The dielectric results highlight the probable crosslinking effect of irradiation between the collagen and the peptides with a chain dynamics similar to the pure collagen one. Indeed, it is known that irradiation can cause a crosslink effect. These preliminary analyses are quite promising for the conception of a new type of biological matrix. In order to optimize the properties of this new material, analyses will be made with less harmful ultraviolet irradiation.
Keywords :
biochemistry; biomedical materials; biomolecular effects of radiation; differential scanning calorimetry; photochemistry; prosthetics; proteins; thermally stimulated currents; biological matrix molecular mobility; biological matrix structure; collagen denaturation temperature; collagen triple helix; collagen-peptide biological matrix; crosslinking effect; thermal analysis; ultraviolet irradiation; Biological materials; Biology; Biomedical engineering; Cardiology; Chemical processes; Dielectrics; Fibroblasts; Peptides; Polymers; Temperature;
Conference_Titel :
Electrets, 2008. ISE-13. 13th International Symposium on
Conference_Location :
Tokyo
Print_ISBN :
978-1-4244-1850-3
Electronic_ISBN :
978-1-4244-1851-0
DOI :
10.1109/ISE.2008.4814084
