DocumentCode :
31498
Title :
Noninvasive and Nonocclusive Blood Pressure Estimation Via a Chest Sensor
Author :
Sola, Josep ; Proenca, Martin ; Ferrario, D. ; Porchet, Jacques-Andre ; Falhi, Abdessamad ; Grossenbacher, Olivier ; Allemann, Yves ; Rimoldi, Stefano F. ; Sartori, Claudio
Author_Institution :
Centre Suisse d´Electron. et de Microtecnique (CSEM), Neuchatel, Switzerland
Volume :
60
Issue :
12
fYear :
2013
fDate :
Dec. 2013
Firstpage :
3505
Lastpage :
3513
Abstract :
The clinical demand for a device to monitor blood pressure (BP) in ambulatory scenarios with minimal use of inflation cuffs is increasing. Based on the so-called pulse wave velocity (PWV) principle, this paper introduces and evaluates a novel concept of BP monitor that can be fully integrated within a chest sensor. After a preliminary calibration, the sensor provides nonocclusive beat-by-beat estimations of mean arterial pressure (MAP) by measuring the pulse transit time (PTT) of arterial pressure pulses travelling from the ascending aorta toward the subcutaneous vasculature of the chest. In a cohort of 15 healthy male subjects, a total of 462 simultaneous readings consisting of reference MAP and chest PTT were acquired. Each subject was recorded at three different days: D, D+3, and D+14. Overall, the implemented protocol induced MAP values to range from 80 ± 6 mmHg in baseline, to 107 ± 9 mmHg during isometric handgrip maneuvers. Agreement between reference and chest-sensor MAP values was tested by using intraclass correlation coefficient (ICC = 0.78) and Bland-Altman analysis (mean error = 0.7 mmHg, standard deviation = 5.1 mmHg). The cumulative percentage of MAP values provided by the chest sensor falling within a range of ±5 mmHg compared to reference MAP readings was of 70%, within ±10 mmHg was of 91%, and within ±15 mmHg was of 98%. These results point at the fact that the chest sensor complies with the British Hypertension Society requirements of Grade A BP monitors, when applied to MAP readings. Grade A performance was maintained even two weeks after having performed the initial subject-dependent calibration. In conclusion, this paper introduces a sensor and a calibration strategy to perform MAP measurements at the chest. The encouraging performance of the presented technique paves the way toward an ambulatory compliant, continuous, and nonocclusive BP monitoring system.
Keywords :
biomedical equipment; blood pressure measurement; blood vessels; calibration; cardiovascular system; medical disorders; patient monitoring; Bland-Altman analysis; MAP measurements; MAP readings; PWV principle; aorta; arterial pressure; arterial pressure pulses; blood pressure monitoring; chest sensor; chest-sensor MAP values; grade A BP monitoring; grade A performance; healthy male subjects; inflation cuffs; intraclass correlation coefficient; isometric handgrip maneuvers; noninvasive blood pressure estimation; nonocclusive BP monitoring system; nonocclusive beat-beat estimations; nonocclusive blood pressure estimation; pulse transit time; pulse wave velocity principle; sensor strategy; standard deviation; subcutaneous vasculature; subject-dependent calibration; Arteries; Atmospheric measurements; Blood pressure; Calibration; Current measurement; Estimation; Particle measurements; Ambulatory; blood pressure (BP); impedance-cardiography (ICG); noninvasive; nonocclusive; photoplethysmography (PPG); pulse wave velocity (PWV);
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/TBME.2013.2272699
Filename :
6557001
Link To Document :
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