Study on Antimicrobial and Antioxidant Activity of Exacts from Agrimonia pilosa Ledeb

Author

Wang Bao-Qing ; Jin Zhe-xiong

Author_Institution

Coll. of Pharmacy, Harbin Univ. of Commerce, Harbin, China

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

4

Abstract

Abstract-Aim: To study the antimicrobial and antioxidant activity of the extracts from Chinese traditional medicine-Agrimonia Pilosa Ledeb. Method: The minimum inhibitory concentration (MIC) value and minimum bactericidal concentration (MBC) value of acetone extracts and methanol extracts from Agrimonia Pilosa Ledeb against bacteria , yeasts and fungi were tested by solid agar dilution method, for their antioxidant activity using scavenging activity of DPPH (1-diphenyl-2-picrylhydrazyl)radical method. Result: this study showed that acetone extract from Agrimonia Pilosa Ledeb was found to possess better antimicrobial activities compared with methanol extract. The acetone extract includes many tannin components is possible reason. In the DPPH system, the antioxidant activity of the acetone extracts was superior to that of the methanol extracts, IC50 values were 48.41 and 55.69 μg/mL, respectively. Such results might be attributed to the synergistic effects of the components .

Keywords

biochemistry; biological techniques; botany; cellular biophysics; microorganisms; molecular biophysics; pharmaceuticals; 1-diphenyl-2-picrylhydrazyl; Agrimonia pilosa Ledeb; Chinese traditional medicine; DPPH radical method; IC50 values; acetone extracts; antimicrobial activity; antioxidant activity; fungi; mass 48.41 mug; mass 55.69 mug; methanol extracts; minimum bactericidal concentration; minimum inhibitory concentration; scavenging activity; solid agar dilution method; synergistic effects; tannin components; yeasts; Business; Capacitive sensors; Educational institutions; Electrons; Fungi; Liver diseases; Methanol; Microorganisms; Microwave integrated circuits; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5518022

Filename

5518022