DocumentCode
3156018
Title
The Effect of Mono- and Di-Methylation of H3K4 on Transcription Might Be Associated with Gene Length
Author
Deng, Yangyang ; Dai, Xianhua
Author_Institution
Dept. of Electron. & Commun. Eng., Sun Yat-Sen Univ., Guangzhou, China
fYear
2010
fDate
18-20 June 2010
Firstpage
1
Lastpage
4
Abstract
We compared the distribution of methylation of histone H3 lysine 4 on genes of different lengths. The result shows that the mono- and di-methylation present different distribution patterns on genes with different lengths. Furthermore, these two methylations exhibit distinct correlations with expression when gene length is different. Our results suggest that the gene length might play a role in the effect of these two modifications on transcription.
Keywords
biochemistry; biological techniques; cellular biophysics; genetics; molecular biophysics; H3K4; dimethylation; gene distribution patterns; gene length; histone H3 lysine 4; monomethylation; transcription; Amino acids; Fungi; Gene expression; Information science; Maintenance engineering; Probability distribution; Recruitment; Region 5; Region 7; Sun;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on
Conference_Location
Chengdu
ISSN
2151-7614
Print_ISBN
978-1-4244-4712-1
Electronic_ISBN
2151-7614
Type
conf
DOI
10.1109/ICBBE.2010.5518227
Filename
5518227
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