Integrated current readout circuit and DMFET array for label-free detection of cancer marker

Author

Im, Maesoon ; Ahn, Jae-Hyuk ; Choi, Yang-Kyu

Author_Institution

Sch. of Electr. Eng. & Comput. Sci., KAIST, Daejeon

Volume

03

fYear

2008

fDate

24-25 Nov. 2008

Abstract

This paper describes a current readout platform designed for dielectric modulated field effect transistor (DMFET) arrays to detect a prostate cancer marker without labeling. A chip of 16 DMFET array has been fabricated as a biosensor cartridge. Standard 0.35 mum CMOS technology has been used to fabricate the readout circuit which includes a current integrator and a 10-bit single-slope analog-to-digital converter (ADC). The prostate cancer marker has been successfully detected by monitoring a change of DMFET current with aid of the fabricated readout circuitry.

Keywords

analogue-digital conversion; biomedical electronics; biosensors; cancer; field effect transistors; readout electronics; ADC; DMFET array; analog-to-digital converter; biosensor cartridge; dielectric modulated field effect transistor; integrated current readout circuit; label-free detection; prostate cancer marker; readout circuit; size 0.35 mum; Analog-digital conversion; Biosensors; CMOS analog integrated circuits; CMOS technology; Cancer detection; Dielectrics; FETs; Labeling; Monitoring; Prostate cancer; biosensor; current integrator; label-free; readout;

fLanguage

English

Publisher

ieee

Conference_Titel

SoC Design Conference, 2008. ISOCC '08. International

Conference_Location

Busan

Print_ISBN

978-1-4244-2598-3

Electronic_ISBN

978-1-4244-2599-0

Type

conf

DOI

10.1109/SOCDC.2008.4815752

Filename

4815752