Medical Image Analysis for Image Guided Therapy

The field of image guided therapy has advanced dramatically over the past decade. Innovations in imaging and image analysis have enabled key improvements in a) preoperative planning, b) intraoperative targeting, navigation and control, and c) postoperative assessment. We describe recent algorithmic advances that have enabled enhanced planning of the neurosurgical trajectory from preoperative structural, functional and diffusion tensor MRI, enabled image guided monitoring and navigation based on intraoperative MRI and nonrigid registration for multi-modality fusion with preoperative images, and enabled quantification of postoperative tumor resection through image segmentation.