Studies on cantilever based triglyceride biosensor

Author

Fernandez, Renny Edwin ; Soma Sekhar, B.V. ; Bhattacharya, Enakshi ; Chadha, Anju

Author_Institution

Indian Inst. of Technol. Madras, Chennai

fYear

2007

fDate

16-20 Dec. 2007

Firstpage

690

Lastpage

693

Abstract

We report detection of micromolar levels of triglycerides using surface micromachined polysilicon cantilever beams. Enzymatic hydrolysis of triglycerides produces glycerol which alters the viscosity and density of the solution. This affects the dynamic properties of cantilever beams immersed in the solution. The change in the resonance frequency of the cantilever beams in the solution is measured using Doppler Vibrometry and the concentration of triglyceride is determined by comparing with a predetermined calibration plot.

Keywords

beams (structures); biosensors; cantilevers; microsensors; viscosity; Doppler vibrometry; cantilever based triglyceride biosensor; cantilever beams; enzymatic hydrolysis; glycerol; micromolar levels detection; surface micromachined polysilicon cantilever beams; viscosity; Biosensors; Chemicals; Frequency measurement; Laser beams; Monitoring; Resonance; Resonant frequency; Structural beams; Vibrometers; Viscosity; biosensor; microcantilever; resonance frequency; triglyceride; vibrometer;

fLanguage

English

Publisher

ieee

Conference_Titel

Physics of Semiconductor Devices, 2007. IWPSD 2007. International Workshop on

Conference_Location

Mumbai

Print_ISBN

978-1-4244-1728-5

Electronic_ISBN

978-1-4244-1728-5

Type

conf

DOI

10.1109/IWPSD.2007.4472613

Filename

4472613