DocumentCode :
3175074
Title :
Incorporating blood pressure load into an elastomechanical ventricular mod
Author :
Mohr, Mb ; Schnell, Rr ; Seemann, G. ; Sachse, FB ; Dössel, O.
Author_Institution :
Inst. of Biomed. Eng., Karlsruhe Univ.
fYear :
2005
fDate :
25-28 Sept. 2005
Firstpage :
307
Lastpage :
310
Abstract :
Elastomechanical modeling constitutes an essential step for realistic computer simulations of the cardiac system. The deformation of tissue effects e.g. cellular electrophysiology, which is commonly neglected in electrophysiological simulations due to the lack of efficient mechanical models. This work focuses on extending a mechanical deformation model by including blood pressure as endocardial boundary condition. Four phases are distinguished in a normal heart cycle: isovolumic contraction, isotonic contraction, isometric relaxation, and isotonic relaxation. The first three phases were modeled. The methods modeling intraventricular pressure corresponding to contraction phases are illustrated, applied, and discussed. Simulation results show that the mechanical model is capable of incorporating a pressure load leading to a more realistic contraction behavior. Furthermore, the ejection curve resembles in closer detail measured data
Keywords :
bioelectric phenomena; biomechanics; cardiology; cellular biophysics; deformation; haemodynamics; blood pressure; cardiac system; cellular electrophysiology; ejection curve; elastomechanical ventricular model; electrophysiological simulation; endocardial boundary condition; heart cycle; intraventricular pressure; isometric relaxation; isotonic contraction; isotonic relaxation; isovolumic contraction; mechanical deformation model; realistic computer simulation; tissue deformation; Blood pressure; Boundary conditions; Cardiology; Computational modeling; Computer simulation; Deformable models; Ellipsoids; Heart; Myocardium; Valves;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computers in Cardiology, 2005
Conference_Location :
Lyon
Print_ISBN :
0-7803-9337-6
Type :
conf
DOI :
10.1109/CIC.2005.1588098
Filename :
1588098
Link To Document :
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