DocumentCode
3175074
Title
Incorporating blood pressure load into an elastomechanical ventricular mod
Author
Mohr, Mb ; Schnell, Rr ; Seemann, G. ; Sachse, FB ; Dössel, O.
Author_Institution
Inst. of Biomed. Eng., Karlsruhe Univ.
fYear
2005
fDate
25-28 Sept. 2005
Firstpage
307
Lastpage
310
Abstract
Elastomechanical modeling constitutes an essential step for realistic computer simulations of the cardiac system. The deformation of tissue effects e.g. cellular electrophysiology, which is commonly neglected in electrophysiological simulations due to the lack of efficient mechanical models. This work focuses on extending a mechanical deformation model by including blood pressure as endocardial boundary condition. Four phases are distinguished in a normal heart cycle: isovolumic contraction, isotonic contraction, isometric relaxation, and isotonic relaxation. The first three phases were modeled. The methods modeling intraventricular pressure corresponding to contraction phases are illustrated, applied, and discussed. Simulation results show that the mechanical model is capable of incorporating a pressure load leading to a more realistic contraction behavior. Furthermore, the ejection curve resembles in closer detail measured data
Keywords
bioelectric phenomena; biomechanics; cardiology; cellular biophysics; deformation; haemodynamics; blood pressure; cardiac system; cellular electrophysiology; ejection curve; elastomechanical ventricular model; electrophysiological simulation; endocardial boundary condition; heart cycle; intraventricular pressure; isometric relaxation; isotonic contraction; isotonic relaxation; isovolumic contraction; mechanical deformation model; realistic computer simulation; tissue deformation; Blood pressure; Boundary conditions; Cardiology; Computational modeling; Computer simulation; Deformable models; Ellipsoids; Heart; Myocardium; Valves;
fLanguage
English
Publisher
ieee
Conference_Titel
Computers in Cardiology, 2005
Conference_Location
Lyon
Print_ISBN
0-7803-9337-6
Type
conf
DOI
10.1109/CIC.2005.1588098
Filename
1588098
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