• DocumentCode
    3175074
  • Title

    Incorporating blood pressure load into an elastomechanical ventricular mod

  • Author

    Mohr, Mb ; Schnell, Rr ; Seemann, G. ; Sachse, FB ; Dössel, O.

  • Author_Institution
    Inst. of Biomed. Eng., Karlsruhe Univ.
  • fYear
    2005
  • fDate
    25-28 Sept. 2005
  • Firstpage
    307
  • Lastpage
    310
  • Abstract
    Elastomechanical modeling constitutes an essential step for realistic computer simulations of the cardiac system. The deformation of tissue effects e.g. cellular electrophysiology, which is commonly neglected in electrophysiological simulations due to the lack of efficient mechanical models. This work focuses on extending a mechanical deformation model by including blood pressure as endocardial boundary condition. Four phases are distinguished in a normal heart cycle: isovolumic contraction, isotonic contraction, isometric relaxation, and isotonic relaxation. The first three phases were modeled. The methods modeling intraventricular pressure corresponding to contraction phases are illustrated, applied, and discussed. Simulation results show that the mechanical model is capable of incorporating a pressure load leading to a more realistic contraction behavior. Furthermore, the ejection curve resembles in closer detail measured data
  • Keywords
    bioelectric phenomena; biomechanics; cardiology; cellular biophysics; deformation; haemodynamics; blood pressure; cardiac system; cellular electrophysiology; ejection curve; elastomechanical ventricular model; electrophysiological simulation; endocardial boundary condition; heart cycle; intraventricular pressure; isometric relaxation; isotonic contraction; isotonic relaxation; isovolumic contraction; mechanical deformation model; realistic computer simulation; tissue deformation; Blood pressure; Boundary conditions; Cardiology; Computational modeling; Computer simulation; Deformable models; Ellipsoids; Heart; Myocardium; Valves;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computers in Cardiology, 2005
  • Conference_Location
    Lyon
  • Print_ISBN
    0-7803-9337-6
  • Type

    conf

  • DOI
    10.1109/CIC.2005.1588098
  • Filename
    1588098