Continuous cardiac output monitoring in humans by non-invasive arterial blood pressure waveform analysis

We have recently introduced a novel technique for continuously monitoring changes in cardiac output (CO) by long time interval analysis of a peripheral arterial blood pressure (ABP) waveform. We have tested the technique with respect to invasive peripheral ABP waveforms obtained from animals and critically ill patients, and our CO estimates showed strong agreement with highly invasive CO measurements. Here, we present a comparison of the application of the technique to non-invasive finger ABP waveforms with reference Doppler ultrasound CO measurements in ten healthy humans during pharmacological and postural interventions. We report an overall CO error of 15.1%