Title :
A model-based control protocol for transition from ICU to HDU: Robustness analysis
Author :
Razak, Normy N. ; Chase, J. Geoffrey ; Suhaimi, Fatanah M. ; Shaw, Geoffrey M. ; Jamaluddin, Ummu
Author_Institution :
Univ. Tenaga Nasional, Kajang, Malaysia
Abstract :
The robustness of a model-based control protocol as a less intensive TGC protocol using insulin Glargine for provision of basal insulin is simulated in this study. To quantify the performance and robustness of the protocol to errors, namely physiological variability and sensor errors, an in-silico Monte Carlo analysis is performed. Actual patient data from Christchurch Hospital, New Zealand were used as virtual trial patients.
Keywords :
Monte Carlo methods; medical control systems; robust control; ICU-HDU transition; TGC protocol; basal insulin; high dependency units; in-silico Monte Carlo analysis; insulin Glargine; model-based control protocol; patient data; physiological variability; robustness analysis; sensor errors; virtual trial patients; Insulin; Monte Carlo methods; Physiology; Plasmas; Protocols; Robustness; Sugar; Monte Carlo; less critical patients; model-based protocol; tight glycaemic control;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6609473