Title :
Development of automated 3-dimensional tissue fabrication system Tissue factory - Automated cell isolation from tissue for regenerative medicine
Author :
Kubo, Hiroshi ; Shioyama, T. ; Oura, M. ; Suzuki, A. ; Ogawa, Tomomi ; Makino, Hiroaki ; Takeda, Shigeki ; Kino-oka, M. ; Shimizu, Tsuyoshi ; Okano, Teruo ; Yamamori, Shinji
Author_Institution :
Nihon Kohden Corp., Tokyo, Japan
Abstract :
We have developed a new automated cell isolation system as one of the modules of automated cell sheet production system named Tissue-Factory (T-Factory). This system enables isolation of the target cells from tissue. Using this new system, we successfully isolated skeletal myoblast from skeletal muscle tissue. The cell isolation system makes us stably prepare cell suspension from each tissue automatically and safely. Isolation of skeletal myoblasts will contribute to labor-saving cell cultivation and operational stability, and lead further process in tissue engineering and regenerative medicine.
Keywords :
cellular biophysics; muscle; tissue engineering; automated 3-dimensional tissue fabrication system; automated cell isolation system; automated cell sheet production system; cell suspension; labor-saving cell cultivation; regenerative medicine; skeletal muscle tissue; skeletal myoblast cell isolation; tissue engineering; tissue factory; tissue target cells; Animals; Educational institutions; Fabrication; Manuals; Muscles; Suspensions; Tissue engineering;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6609511