• DocumentCode
    3191084
  • Title

    In-vitro quantification of rat liver viscoelasticity with shear wave dispersion ultrasound vibrometry

  • Author

    Yan-rong Guo ; Xin Chen ; Haoming Lin ; Xinyu Zhang

  • Author_Institution
    Dept. of Biomed. Eng., Shenzhen Univ., Shenzhen, China
  • fYear
    2013
  • fDate
    3-7 July 2013
  • Firstpage
    1915
  • Lastpage
    1918
  • Abstract
    As a new imaging method for tissue mechanical properties, ultrasound elastography has always been the research focus in the field of medical ultrasound imaging ever since it has been proposed. This paper developed an ultrasound viscoelasticity measurement system based on shear wave dispersion ultrasound vibrometry (SDUV). This system applied acoustic radiation force to excite harmonic vibration in soft tissue. The propagation of the shear wave induced by the vibration was detected and the tissue viscoelasticity properties were calculated. Based on this system, rat livers were measured in vitro. The results shows that the system can measure the viscoelasticity reliably, offering a potential alternative to diagnosis of liver fibrosis.
  • Keywords
    biological tissues; biomechanics; biomedical measurement; biomedical ultrasonics; diseases; elastic waves; liver; vibration measurement; viscoelasticity; SDUV; acoustic radiation force; harmonic vibration; in vitro quantification; liver fibrosis; medical ultrasound imaging; rat liver viscoelasticity; shear wave dispersion ultrasound vibrometry; tissue mechanical properties; ultrasound elastography; ultrasound viscoelasticity measurement system; Acoustics; Biomedical imaging; Elasticity; Liver; Ultrasonic imaging; Vibrations; Acoustic radiation force; Liver fibrosis; Shear wave dispersion ultrasound vibration; Ultrasound elastography; Viscoelasticity;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
  • Conference_Location
    Osaka
  • ISSN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/EMBC.2013.6609900
  • Filename
    6609900