Title :
A computer model of ST changes in subendocardial ischaemia
Author :
Li, C.Y. ; Kilpatrick, D. ; Johnston, P.
Author_Institution :
Div. of Clinical Sci., Tasmania Univ., Hobart, Tas., Australia
fDate :
31 Oct-3 Nov 1996
Abstract :
We describe a computer model of the epicardial and endocardial potentials during partial myocardial ischaemia. The heart is represented by a block with both left and right ventricles included. A bidomain model is used to represent the myocardium. The results show that when the ischaemic region reaches the septum, the current mainly goes through blood which changes the epicardial potential distribution dramatically. The negative epicardial potential is mainly due to current flowing across the boundary of the ischaemia on the free wall. All coronary arteries share territorial boundaries over the free wall, which results in epicardial ST depression over the boundary no matter which territory is made ischaemic. The simulations are in good agreement with measurements in an animal model
Keywords :
bioelectric potentials; electrocardiography; medical signal processing; muscle; physiological models; ECG; ST changes; action potentials; bidomain model; computer model; coronary arteries; endocardial potentials; epicardial ST depression; epicardial potentials; free wall; heart muscle slab; partial myocardial ischaemia; septum; subendocardial ischaemia; territorial boundaries; Animals; Arteries; Blood; Computational modeling; Computer simulation; Conductivity; Heart; Ischemic pain; Muscles; Myocardium;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.647453
