Myocardial ischemia and infarction can be detected by microwave spectroscopy. I. Experimental evidence

Author

Semenov, Serguei Y. ; Svenson, Robert H. ; Dezern, Kathy R. ; Quinn, Michael E. ; Thompson, Michelle ; Tatsis, George P.

Author_Institution

Laser & Appl. Technol. Lab., Carolinas Med. Center, Charlotte, NC, USA

Volume

4

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

1361

Abstract

The two dimensional (2D) microwave tomographic system has been constructed. The cross sectional static and dynamic images of the canine explanted heart have been reconstructed. It is our hypothesis that microwave spectroscopy (multifrequency probing) is a sensitive indicator of myocardial ischemia and infarction. The specific aim of this investigation is to evaluate our hypothesis and quantify the changes in the dielectric properties of the myocardium as a function of the degree of ischemia and infarction. Various experiments were conducted using canine: 100% left anterior descending coronary artery (LAD) long time occlusion, 100% LAD short time occlusion/reperfusion sequence, partial LAD flow reduction, chronic myocardium infarction (MI) (5 days, 2 weeks, 5 months). It has been experimentally proven that microwave spectroscopy is a sensitive indicator of the myocardial ischemia and infarction

Keywords

bioelectric potentials; cardiology; computerised tomography; image reconstruction; medical image processing; microwave imaging; microwave spectroscopy; muscle; 2D microwave tomographic system; canine explanted heart; cross sectional images; dielectric properties; dynamic images; left anterior descending coronary artery; long time occlusion; microwave spectroscopy; multifrequency probing; myocardial infarction; myocardial ischemia; partial flow reduction; reconstructed images; short time occlusion/reperfusion sequence; static images; Dielectrics; Heart; Image reconstruction; Ischemic pain; Microwave technology; Myocardium; Probes; Spectroscopy; Temperature sensors; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.647454

Filename

647454