Visual evoked potential characterization of rabbit animal model for retinal prosthesis research

Author

Khraiche, M.L. ; El Emam, Sharif ; Akinin, Abraham ; Cauwenberghs, Gert ; Freeman, William ; Silva, G.A.

Author_Institution

Dept. of Bioeng., Univ. of California, San Diego, La Jolla, CA, USA

fYear

2013

fDate

3-7 July 2013

Firstpage

3539

Lastpage

3542

Abstract

Visual evoked potentials (VEP) are used to confirm the function of prosthetic devices designed to stimulate retinas with damaged photoreceptors in vivo. In this work, we focus on methods and experimental consideration for recording visual evoked potential in rabbit models and assesses the use for retinal prosthesis research. We compare both invasive and noninvasive methods for recording VEPs, the response of the rabbit retina to various light wavelengths and intensities, focal vs. full field stimulation, and the effect of light bleaching on the retinal response.

Keywords

biomedical materials; eye; optical saturable absorption; prosthetics; visual evoked potentials; focal stimulation; full field stimulation; light bleaching effect; light intensity; light wavelength; photoreceptor; prosthetic device; rabbit animal model; rabbit retina stimulation; retinal prosthesis research; visual evoked potential characterization; visual evoked potential recording; Bleaching; Electrodes; Prosthetics; Rabbits; Retina; Visualization;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE

Conference_Location

Osaka

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2013.6610306

Filename

6610306